Unfortunately this type of logic is not possible with Patch Manager because it is impossible to filter on non-existent data. The inventory captures what isInstalled.
The best option you can work from here is to export the list of machines that do have a particular application installed into Excel, Access, or SQL Server, and then run an outer join against the full list of machine names that were inventoried. This will allow you to obtain a list of the machines that are in the list but do not have the selected application installed..